Biotechnology

From microfluidics to DNA sequencing chips, and from microneedles to neural probes, Atomica offers decades of experience bringing our customers’ biotechnologies to life.

Atomica is proud to partner with innovative companies on missions to cure disease. We bring 20+ years of experience to the design, process development, and volume fabrication of microsystems targeted at life science applications. You could say we know a thing or two because we’ve seen a thing or two. From drug-delivery devices to neural probes, cell sorters to biosensors, DNA synthesis to sequencing, Atomica has the capabilities to bring our customers’ biotechnologies to life.

Applications

Drug Delivery

The days of forcing a patient to adhere to a regimented schedule for a daily medication before or after meals are fading. At the cutting edge of today’s applications, implanted and transdermal bioMEMS devices are enabling remotely configured, automated delivery of drug doses over long time periods.

Atomica’s experience with micro-needles, MEMS reservoirs, and many types of micro-pumps and actuators is a crucial foundation for getting drug-delivery devices to market – faster.

Molecular Diagnostics

Molecular diagnostics determine the presence and the amount of a biological molecular marker (biomarkers such as DNA or protein, as measured through an antigen-binding event or fluorescent or mass signals) that provides information about the presence of a pathogen, an individual’s disease state, risk factors, or treatment effectiveness. An increasing variety of commercial molecular diagnostics products harness the power of microfluidics and bioMEMS to provide rapid, accurate, point-of-care (or even at-home) detection of biomarkers. Excitingly, some of these technologies and products are displacing traditional, slower lab-based analyses.

Atomica brings critical experience and capabilities for manufacturing virtually all types of diagnostic chips. Unlike CMOS fabs, Atomica can handle diverse substrates (Si, glass, piezo materials, III-V, and more), process and deposit non-CMOS materials (such as Au, Ag, Sn, Pt, Ru, and other noble metals, polymers such as parylene, graphene, and even biological agents), and perform a broad array of wafer processing, including deep silicon etches, wafer bonding, atomic layer deposition, and more.

Cell Therapy and Cytometry

We are on the cusp of a revolution in medicine due to the arrival of next-generation cell technologies such as CAR-T and stem-cell therapies. The ability to isolate, culture, manipulate, and genetically re-program specific cell populations is bringing us ever closer to curing cancer and other diseases. These emerging fields require new types of microfluidic devices that identify, sort, process, porate, filter, and move these cells at high speed without damaging them.

Atomica has the capabilities and experience to help innovative companies design, develop, and fabricate microfluidic devices to make life-changing treatments a reality. During cell therapy, cells are delivered via injection to an organ or injury, where they replace or help repair damaged tissue. These cells, which can come from the patient or from another donor, must be sorted and processed to be appropriate for therapy. Read this case study to learn about how Atomica partnered with Miltenyi to develop a gentle, ultrafast microfluidic cell valve that enables cell sorting with high cell purity and viability.

Explore Atomica’s Biotechnology Platforms that enable rapid prototyping and scalable production of your device.

microfluidic-channel

Microfluidic Channel Platform

Learn how Atomica’s Microarray platform allows customers to cost-effectively leverage standard structures to facility rapid prototyping and scalable production.

Get the Guide

microfluidic-pump

Microfluidic Pump Platform

Discover Atomica’s Microfluidic Pump platform, which lets customers utilize standardized structures to streamline rapid prototyping and scalable manufacturing.

Get the Guide

microfluidic-valve

Microfluidic Valve Platform

See how Atomica’s Microfluidic Valve platform empowers customers by offering standard structures for efficient prototyping and production scalability.

Get the Guide

microneedle

Microneedle Platform

Uncover how Atomica’s Microneedle platform provides customers with access to standard structures, facilitating faster prototyping and scalable production.

Get the Guide

microarray

Microarray Platform

Find out how Atomica’s Microarray platform supports customers in leveraging standard structures to accelerate prototyping and expand production scalability.

Get the Guide

Why Atomica?

Atomica focuses on the success of our customers’ products, with rapid prototyping and scalable production. We are a leader in microfabrication, including photonics, sensors, biotechnology, and MEMS. We provide customers device optimization, faster speed to market, and cost-efficient fabrication. Atomica operates a 30,000-square-foot class 100 cleanroom near Santa Barbara, California, supporting a wide range of capabilities and materials with ISO 9001 certification and ITAR registration. We leverage sophisticated process control analytics, artificial intelligence inspection, advanced metrology, and proprietary fab operations systems to maximize efficiency.