Biotechnology
From microfluidics to DNA sequencing chips, and from microneedles to neural probes, Atomica offers decades of experience bringing our customers’ biotechnologies to life.
Applications
Drug Delivery
The days of forcing a patient to adhere to a regimented schedule for a daily medication before or after meals are fading. At the cutting edge of today’s applications, implanted and transdermal bioMEMS devices are enabling remotely configured, automated delivery of drug doses over long time periods.
Atomica’s experience with micro-needles, MEMS reservoirs, and many types of micro-pumps and actuators is a crucial foundation for getting drug-delivery devices to market – faster.
Molecular Diagnostics
Molecular diagnostics determine the presence and the amount of a biological molecular marker (biomarkers such as DNA or protein, as measured through an antigen-binding event or fluorescent or mass signals) that provides information about the presence of a pathogen, an individual’s disease state, risk factors, or treatment effectiveness. An increasing variety of commercial molecular diagnostics products harness the power of microfluidics and bioMEMS to provide rapid, accurate, point-of-care (or even at-home) detection of biomarkers. Excitingly, some of these technologies and products are displacing traditional, slower lab-based analyses.
Atomica brings critical experience and capabilities for manufacturing virtually all types of diagnostic chips. Unlike CMOS fabs, Atomica can handle diverse substrates (Si, glass, piezo materials, III-V, and more), process and deposit non-CMOS materials (such as Au, Ag, Sn, Pt, Ru, and other noble metals, polymers such as parylene, graphene, and even biological agents), and perform a broad array of wafer processing, including deep silicon etches, wafer bonding, atomic layer deposition, and more.
Cell Therapy and Cytometry
We are on the cusp of a revolution in medicine due to the arrival of next-generation cell technologies such as CAR-T and stem-cell therapies. The ability to isolate, culture, manipulate, and genetically re-program specific cell populations is bringing us ever closer to curing cancer and other diseases. These emerging fields require new types of microfluidic devices that identify, sort, process, porate, filter, and move these cells at high speed without damaging them.
Atomica has the capabilities and experience to help innovative companies design, develop, and fabricate microfluidic devices to make life-changing treatments a reality. During cell therapy, cells are delivered via injection to an organ or injury, where they replace or help repair damaged tissue. These cells, which can come from the patient or from another donor, must be sorted and processed to be appropriate for therapy. Read this case study to learn about how Atomica partnered with Miltenyi to develop a gentle, ultrafast microfluidic cell valve that enables cell sorting with high cell purity and viability.
Explore Atomica’s Biotechnology Platforms that enable rapid prototyping and scalable production of your device.
Why Atomica?
Atomica focuses on the success of our customers’ products, with rapid prototyping and scalable production. We are a leader in microfabrication, including photonics, sensors, biotechnology, and MEMS. We provide customers device optimization, faster speed to market, and cost-efficient fabrication. Atomica operates a 30,000-square-foot class 100 cleanroom near Santa Barbara, California, supporting a wide range of capabilities and materials with ISO 9001 certification and ITAR registration. We leverage sophisticated process control analytics, artificial intelligence inspection, advanced metrology, and proprietary fab operations systems to maximize efficiency.