Biotechnology platform

Biotechnology Microdevices Platform

Integrate fluid handling, biological interfaces and sensing in manufacturable devices

The Biotechnology Microdevices Platform brings together microfluidic channels, pumps, valves, microneedles, microarrays, sensors and wafer-level packaging. Customers combine these established subplatforms with custom layers, coatings and interfaces to create an integrated device. Development considers fluid behavior, surface chemistry, biological compatibility and package integrity, connecting the device’s biological function with repeatable fabrication at scale.

Additional and custom biotechnology development

Some biotechnology devices need specialized geometries, materials or interfaces beyond the platform’s standard elements. Atomica combines reusable processes with custom development for features such as assay-specific surfaces, porous membranes, optical windows and integrated electrodes.

We assess sample and reagent compatibility, device interfaces and fabrication requirements together, identifying which established processes fit and where additional development is needed.

Applications

Genomics and molecular analysis

Sample preparation, amplification and detection on integrated biochips

Genetic analysis relies on consistent sample preparation, extraction, amplification and detection. Integrated biochips can bring these steps closer together, reducing manual handling and the volumes of samples and reagents required.

Atomica combines microfluidic pathways, reaction chambers and patterned microarray surfaces, with thermal and optical interfaces developed around the analysis workflow and assay chemistry.

Point-of-care diagnostics

Sample handling, reactions and detection in compact test cartridges

Point-of-care diagnostics bring testing closer to the patient by combining sample handling, reactions and detection in compact cartridges. The device must sequence fluids reliably and present a readable signal to the instrument.

Atomica integrates channels, valves, chambers and sensing interfaces around the assay, with material selection, surface treatments and packaging developed for the sample and readout method.

Drug delivery devices

Microneedles, pumps and valves for transdermal, wearable and implantable delivery

Transdermal patches and wearable or implantable delivery devices offer ways to administer therapies with greater control over where and when a dose is delivered. Their operation depends on reliable fluid movement and tissue interfaces.

Atomica combines microneedles, reservoirs, pumps, valves and membranes, developing geometry, flow control and packaging around the formulation, delivery method and mechanical requirements.

Cell processing and analysis

Isolate, sort and filter cells while preserving viability

Cell analysis and therapy workflows require cells to be isolated, sorted, filtered and moved while preserving viability. Microfluidic devices can bring these operations into controlled pathways, supporting consistent sample handling.

Atomica develops channels, valves and filtration features around the cell population and process, considering flow conditions, surface compatibility and integration with detection systems.

Organ-on-chip and drug discovery

Controlled environments for studying cells and tissues

Organ-on-chip and screening systems create controlled environments for studying cellular behavior and responses to potential therapies. These tools need to deliver nutrients, remove waste and support observation over time.

Atomica integrates culture chambers, channels, porous membranes and sensing or optical interfaces, with geometry, coatings and flow conditions developed around the biological model and research workflow.

Wearable and implantable sensors

Sensing and sampling close to the body

Wearable and implantable devices bring physiological measurements and sampling closer to the body. Compact sensors must interface with fluids or tissue while connecting reliably to the electronics that collect and interpret signals.

Atomica develops diaphragms, pressure-sensing elements, sampling features and protective packages, with materials and interfaces evaluated for the intended contact conditions and device lifetime.

Why Atomica?

A manufacturable path from prototype to production

Atomica is a U.S.-based microfabrication foundry that turns advanced device concepts into manufacturable, scalable hardware — and its advantage is not a single process but a system that de-risks the path from first prototype to volume.

30,000 sq ft cleanroom · Class 100 · ISO 9001 certified · ITAR registered · Santa Barbara, USA

1

Engineering Collaboration

Atomica works as an engineering partner across design, materials, fabrication, and testing, bringing diverse expertise together to optimize each micro-scale device. That collaboration is what yields better products, lower cost, faster time-to-market, and quicker adaptation to emerging technologies.

2

Process Standardization

Standardized processes give a clear framework for fabrication, scaling, and quality control. This is what delivers the consistency, quality, and efficiency that reliable, high-performance microdevices require — while supporting regulatory compliance and continuous improvement.

3

Modeling & Simulation

Atomica evaluates designs before fabrication using physics-based modeling, FEA, CFD, AI, and multiphysics simulation. Simulating first reduces prototype iterations, lowers cost, identifies risks early, and improves first-pass success across photonics, sensors, biotech devices, MEMS, and integrated microsystems.

4

AI Optimization (FabOps)

Atomica’s FabOps system applies AI and advanced analytics across wafer inspection, metrology, fab control, and project execution. By integrating equipment, process flows, pricing, projects, and manufacturing — with real-time visibility, lot tracking, and change control — it reduces risk and accelerates programs from prototype to scalable production.

5

Fab Technology

Atomica operates a 30,000 sq ft, class-100 cleanroom near Santa Barbara, California — ISO 9001 certified and ITAR registered. Its full in-house process suite spans photolithography, deposition, dry and wet etch, bonding, plating, metrology, testing, dicing, and planarization, purpose-built for rapid prototyping and scalable production.

Explore Atomica’s in-depth resources to navigate modeling and simulation, rapid prototyping, scalable production, and fab evaluation — all with expert insight.

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Rapid Prototyping Services at Atomica

Uncover our efficient process that turns ideas into working prototypes swiftly, helping you bring innovations to life quickly.

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Scaling Production with Atomica’s Expertise

Explore how our advanced production methods ensure consistent, high-quality, and cost-effective results at every stage of scale.

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Inside Atomica’s Advanced Fab Technology

Take a detailed look at our high-tech capabilities, engineered to support complex, precision-driven microfabrication.

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Selecting the Right Fab for Your Project

Our Fab Evaluation Guide outlines essential criteria, ensuring your project is matched to the best fabrication partner.

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Simulation-Driven Microfabrication

See how modeling and simulation improve performance, lower cost, shorten timelines, and drive better outcomes.

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Next Steps

Developing a biotechnology device? Talk to an Atomica engineer about turning biological performance requirements into a scalable microfabricated device.

Evaluating a microfabrication partner for biotechnology? Download our Fab Evaluation Guide to compare capabilities, processes, and scale-readiness before you commit.